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Glasdegib

CAT: 0931-T6514-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6514-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1095173-27-5
Target
Smo, Hedgehog/Smoothened
Related Pathways
GPCR/G Protein, Stem Cells
Purity
0.9872
Bioactivity
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
Smiles
CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N
Molecular Formula
C21H22N6O
Molecular Weight
374.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C