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RMS5

CAT: 0931-T64223-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64223-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2497686-68-5
Target
Others, P-gp, Apoptosis
Related Pathways
Membrane transporter/Ion channel, Apoptosis, Others, Neuroscience
Bioactivity
RMS5 is a hambanine analogue and a potent P-glycoprotein (P-gp) inhibitor.RMS5 has significant anti-proliferative and cytotoxic effects on cancer cells.RMS5 slightly reduces the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1.RMS3 causes cleavage of PARP, a marker of apoptosis.RMS5 has strong anti-cancer properties. RMS5 has strong anti-cancer properties.
Smiles
O(C)C1=C2C3=C(C=C1OC)CCN(C)[C@]3(CC4=CC(=CS4)OC=5C=CC(C[C@@]6(C7=CC(O2)=C(OC)C=C7CCN6C)[H])=CC5)[H]
Molecular Formula
C35H38N2O5S
Molecular Weight
598.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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