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DPPY

CAT: 0931-T63486-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63486-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2095883-62-6
Target
BTK, Others, EGFR, JAK
Related Pathways
Stem Cells, Others, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
DPPY is a potent inhibitor of PTK that acts on EGFR (IC50<10 nM), BTK (IC50<10 nM), and JAK3 (IC50<10 nM) . DPPY inhibits the proliferation of B-cell lymphoma cells and has potential for investigation in idiopathic pulmonary fibrosis (IPF) .
Smiles
N(C1=NC(NC2=CC=C(NC(CN3CCOCC3)=O)C=C2)=NC=C1Cl)C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C25H26ClN7O3
Molecular Weight
507.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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