MRTX-EX185

• Target:

  Ras|||Kras|||Others

• Related Pathways:

  Others|||MAPK|||GPCR/G Protein

• Bioactivity:

  MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D) . MRTX-EX185 is also capable of binding GDP-loaded HRAS.

• Molecular Formula:

  C33H33FN6O2

• Molecular Weight:

  564.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C