Trimetrexate glucuronate

• Target :

  Antibacterial|||Antifolate|||Others

• Related Pathways :

  Cell Cycle/Checkpoint|||Others|||Microbiology/Virology

• Bioactivity :

  Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, blocking the synthesis of purine nucleotides and thymidylic acid, therefore affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects.

• Smiles :

  O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O.COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

• Molecular Formula :

  C25H33N5O10

• Molecular Weight :

  563.564

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  82952-64-5