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PKRA83

CAT: 0931-T63446-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63446-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1233926-87-8
Target
Others
Related Pathways
Others
Bioactivity
PKRA83 is a potent prokineticin (PK2) antagonist that crosses the blood-brain barrier and competes for PK2 binding to its receptors PKR1 and PKR2. PKRA83 effectively inhibits PK2 receptors and acts on PKR1 (IC50: 5.0 nM) and PKR2 (IC50: 8.2 nM) . PKRA83 exhibits anti-cancer and anti-angiogenic effects.
Smiles
ClC1=C2C(=CC(CN(C(=O)[C@H]3CN(CC4=CC(OC)=C(F)C=C4)CC3)CC(C)C)=C1)OCCCO2
Molecular Formula
C27H34ClFN2O4
Molecular Weight
505.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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