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ULK1-IN-2

CAT: 0931-T63343-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T63343-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2497409-01-3
Target
FAK, Autophagy, AMPK, Apoptosis
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Autophagy, Cytoskeletal Signaling, Apoptosis, Angiogenesis, PI3K/Akt/mTOR signaling
Purity
0.9997
Bioactivity
ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 μM against A549 cells.ULK1-IN-2 can be used for the study of non-small-cell lung cancer.
Smiles
O(C)C1=C(OC)C=C(NC=2N=C(OC3=C(F)C=C(N(=O)=O)C=C3)C(Br)=CN2)C=C1OC
Molecular Formula
C19H16BrFN4O6
Molecular Weight
495.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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