ULK1-IN-2

• Target:

  FAK|||Autophagy|||AMPK|||Apoptosis

• Related Pathways:

  Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Autophagy|||Cytoskeletal Signaling|||Apoptosis|||Angiogenesis|||PI3K/Akt/mTOR signaling

• Purity:

  0.9997

• Bioactivity:

  ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 ?M against A549 cells.ULK1-IN-2 can be used for the study of non-small-cell lung cancer.

• Smiles:

  O(C)C1=C(OC)C=C(NC=2N=C(OC3=C(F)C=C(N(=O)=O)C=C3)C(Br)=CN2)C=C1OC

• Molecular Formula:

  C19H16BrFN4O6

• Molecular Weight:

  495.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2497409-01-3