EGFR-IN-33

CAT: 0931-T63264-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63264-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2711105-59-6

Target

EGFR, Others

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others

Bioactivity

EGFR-IN-33, an acrylamide derivative, is a low-toxicity antitumor agent and a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-33 exhibits potential for the study of EGFR mutation-related diseases.

Smiles

NC1=C2N(C=C(C2=NC=N1)C3CN(C(C=C)=O)CCC3)C4=CC(Cl)=C(OCC5=CC=CC=N5)C=C4

Molecular Formula

C26H25ClN6O2

Molecular Weight

488.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5805936	EGFR-IN-33
275404-01	33-Epichloro-33-desoxyascomycin
228238	Interleukin-33 (IL-33)
MBS6507798-01	Interleukin 33 (IL-33)
sc-80543	EGFR (EGFR.1)
6313/10	A 33
069-02	Cholecystokinin-33 (CCK-33) (Human)
QY-E70214	Canine Interleukin 33 (IL-33)
QY-E40234	Pig Interleukin 33 (IL-33)
RC212-44	IL-33, Interleukin-33, human

EGFR-IN-33

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