OSI-027

CAT: 0931-T6319-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T6319-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

936890-98-1

Target

MTOR, Autophagy, DNA-PK, PI3K

Related Pathways

DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Autophagy

Purity

0.98

Bioactivity

OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1.

Smiles

COc1cccc2=C\C(N=c12)=c1/nc(C2CCC(CC2)C(O)=O)n2NC=NC(N)=c12

Molecular Formula

C21H22N6O3

Molecular Weight

406.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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B1637-5	OSI-027
FO36379-01	OSI 027

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