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R547

CAT: 0931-T6312-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6312-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
741713-40-6
Target
CDK, GSK-3, Apoptosis, PKA
Related Pathways
Cell Cycle/Checkpoint, Stem Cells, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Apoptosis
Purity
0.9984
Bioactivity
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
Smiles
COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N
Molecular Formula
C18H21F2N5O4S
Molecular Weight
441.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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C08782-2mgR547
A11190-50R547 50mg
A11190-5R547 5mg
A11190-500R547 500mg
A11190-1R547 1mg
HY-10014RR547 (Standard)

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