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GPR84 antagonist 3

CAT: 0931-T62918-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62918-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2815263-05-7
Target
Others, GPCR
Related Pathways
Others, Endocrinology/Hormones, GPCR/G Protein
Bioactivity
GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a favorable pharmacokinetic profile, suitable for further research and development [1].
Smiles
C(C=1N=C(C(=NN1)C2=CC=C(CN3CCOCC3)C=C2)C4=CC=CC=C4)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C29H27N5O
Molecular Weight
461.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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