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TDRL-X80

CAT: 0931-T62730-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62730-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
292065-64-6
Target
DNA/RNA Synthesis, Others
Related Pathways
Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA), inhibiting the DNA binding activity of XPA. It acts on single, double, and cisplatin-damaged DNA with IC50 values of 18, 20, and 29 μM in fluorescence polarization (FP) assays and 21, 39, and 28 μM in ELISA assays.
Smiles
CC1=NN(C(=O)C\1=C/C1=CC=C(O1)C1=CC(C(O)=O)=C(Cl)C=C1)C1=CC=CC(=C1)C(O)=O
Molecular Formula
C23H15ClN2O6
Molecular Weight
450.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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