TDRL-X80

• Target:

  DNA/RNA Synthesis|||Others

• Related Pathways:

  Others|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Bioactivity:

  TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA), inhibiting the DNA binding activity of XPA. It acts on single, double, and cisplatin-damaged DNA with IC50 values of 18, 20, and 29 ?M in fluorescence polarization (FP) assays and 21, 39, and 28 ?M in ELISA assays.

• Smiles:

  CC1=NN (C (=O) C\1=C/C1=CC=C (O1) C1=CC (C (O) =O) =C (Cl) C=C1) C1=CC=CC (=C1) C (O) =O

• Molecular Formula:

  C23H15ClN2O6

• Molecular Weight:

  450.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  292065-64-6