JNc-440

• Target :

  Others|||TRP/TRPV Channel|||Potassium Channel

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.

• Smiles :

  O=C(NCCCNC(=O)c1nc2ccccc2c(=O)[nH]1)C(c1ccccc1)c1ccccc1

• Molecular Formula :

  C26H24N4O3

• Molecular Weight :

  440.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1119503-63-7