JNc-440

CAT: 0931-T62543-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T62543-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1119503-63-7
Target
Others|||TRP/TRPV Channel|||Potassium Channel
Related Pathways
Membrane transporter/Ion channel|||Others
Bioactivity
JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.
Smiles
O=C(NCCCNC(=O)c1nc2ccccc2c(=O)[nH]1)C(c1ccccc1)c1ccccc1
Molecular Formula
C26H24N4O3
Molecular Weight
440.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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