JNc-440

• Target:

  Others|||TRP/TRPV Channel|||Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Others

• Bioactivity:

  JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.

• Smiles:

  O=C (NCCCNC (=O) c1nc2ccccc2c (=O) [nH]1) C (c1ccccc1) c1ccccc1

• Molecular Formula:

  C26H24N4O3

• Molecular Weight:

  440.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1119503-63-7