EGFR-IN-56

CAT: 0931-T62458-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T62458-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2477726-83-1

Target

EGFR, Apoptosis, Others

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Apoptosis, Others

Bioactivity

EGFR-IN-56 (Compound 13a) is a potent inhibitor of EGFR, targeting EGFRT790M (IC50: 541.7 nM) and EGFRT790M/L858R (IC50: 132.1 nM), blocking the G2/M phase of the cancer cell cycle and inducing apoptosis.

Smiles

O(C1=C2C(=NC(NC3=CC=C(OC)C=C3)=N1)CCSC2)C4=CC(NC(C=C)=O)=CC=C4

Molecular Formula

C23H22N4O3S

Molecular Weight

434.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19186143-01	EGFR-IN-56
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EGFR-IN-56

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