MELK-8a

• Target :

  Haspin Kinase|||Others|||PDGFR|||MELK

• Related Pathways :

  Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Others

• Bioactivity :

  MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), with an IC50 of 2 nM and an IC50 of 0.42 ?M in cellular assays. MELK is crucial in regulating mitosis in cancer cells.

• Smiles :

  O(CC1CCNCC1)C=2C(=CC=NC2)C3=CN(N=C3)C4=CC=C(C=C4)N5CCN(C)CC5

• Molecular Formula :

  C25H32N6O

• Molecular Weight :

  432.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1922153-17-0