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IMPDH2-IN-2

CAT: 0931-T62338-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T62338-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1434517-02-8
Target
Dehydrogenase, Antibacterial
Related Pathways
Microbiology/Virology, Metabolism
Purity
0.9904
Bioactivity
IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki, app: 14 μM) and a potential anti-tuberculosis agent, exhibiting moderate antibacterial effects with MIC values of 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively.
Smiles
N(C([C@@H](OC1=C(Cl)C(Cl)=CC=C1)C)=O)C=2C=C3C(OC(=N3)C=4C=CN=CC4)=CC2
Molecular Formula
C21H15Cl2N3O3
Molecular Weight
428.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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