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VEGFR-2-IN-25

CAT: 0931-T62314-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62314-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2439096-02-1
Target
Others, VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Others, Angiogenesis
Bioactivity
VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 with an IC50 of 12.1 nM.
Smiles
N(C=1C2=C(N=C(C(NC)=O)N1)C=CC=C2)C3=CC=C(NC(NC4=CC(C)=CC=C4)=O)C=C3
Molecular Formula
C24H22N6O2
Molecular Weight
426.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Vegfr-2-IN-25
CAS Number2439096-02-1
PubChem CID164516871
IUPAC NameN-methyl-4-[4-[(3-methylphenyl)carbamoylamino]anilino]quinazoline-2-carboxamide
Molecular FormulaC24H22N6O2
Molecular Weight426.5
XLogP4
Topological Polar Surface Area108
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count32
Formal Charge0
Complexity638
SMILES
CC1=CC(=CC=C1)NC(=O)NC2=CC=C(C=C2)NC3=NC(=NC4=CC=CC=C43)C(=O)NC
InChI
InChI=1S/C24H22N6O2/c1-15-6-5-7-18(14-15)28-24(32)27-17-12-10-16(11-13-17)26-21-19-8-3-4-9-20(19)29-22(30-21)23(31)25-2/h3-14H,1-2H3,(H,25,31)(H,26,29,30)(H2,27,28,32)
InChIKey
FALXZGBOUDIVJB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Vegfr-2-IN-25
CAS: 2439096-02-1
CID: 164516871
Formula: C24H22N6O2
MW: 426.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight426.5
XLogP34
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass426.18042397
Monoisotopic Mass426.18042397
Topological Polar Surface Area108 Ų
Heavy Atom Count32
Formal Charge0
Complexity638
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T10123-01VEGFR-2-IN-9
T204905-01VEGFR-2-IN-61
T61137-01VEGFR-2-IN-19
T72890-01VEGFR-2-IN-30
T62901-01VEGFR-2-IN-27
T62763-01VEGFR-2-IN-12
T89976-01VEGFR-2-IN-52
T80872-01VEGFR-2-IN-37
T79400-01VEGFR-2-IN-35
T63822-01VEGFR-2-IN-22

Alternative Products

CatalogName
MBS5805002VEGFR-2-IN-25
MBS668224-01VEGFR-2
BA9059-1VEGFR-2-IN-6
C8539-100VEGFR-2-IN-20
BA9055-5VEGFR-2-IN-37
HY-179032VEGFR-2-IN-77
HY-175018VEGFR-2-IN-71
HY-170366VEGFR-2-IN-58
HY-169516VEGFR-2-IN-65
HY-147800VEGFR-2-IN-21

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