PARP-1-IN-2

CAT: 0931-MF-0093315-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0093315-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
684234-55-7
Target
Apoptosis|||Caspase|||PARP
Related Pathways
Proteases/Proteasome|||Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair
Purity
0.9932
Bioactivity
PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM) .PARP-1-IN-2 showed significant antiproliferative activity against the human lung adenocarcinoma epithelial cell line A549 in cellular assays.PARP-1-IN-2 induced apoptosis in A549 cells.
Smiles
Clc1ccc(cc1)-c1nn(CC(=O)Nc2cccc(Cl)c2)c(=O)c2ccccc12
Molecular Formula
C22H15Cl2N3O2
Molecular Weight
424.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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