HS-276

• Target :

  IRAK|||Casein Kinase|||MAPK|||TNF

• Related Pathways :

  Stem Cells|||Metabolism|||Apoptosis|||NF-?B|||Immunology/Inflammation|||MAPK

• Purity :

  0.9881

• Bioactivity :

  HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM) . HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA) .

• Smiles :

  C(CC)N1C=2C(N=C1NC(=O)C3=CC(C(N)=O)=CC=C3)=CC=C(CN4CCCCC4)C2

• Molecular Formula :

  C24H29N5O2

• Molecular Weight :

  419.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2767422-72-8