HS-276

CAT: 0931-T62209-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T62209-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2767422-72-8
Target
IRAK|||Casein Kinase|||MAPK|||TNF
Related Pathways
Stem Cells|||Metabolism|||Apoptosis|||NF-?B|||Immunology/Inflammation|||MAPK
Purity
0.9881
Bioactivity
HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM) . HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA) .
Smiles
C(CC)N1C=2C(N=C1NC(=O)C3=CC(C(N)=O)=CC=C3)=CC=C(CN4CCCCC4)C2
Molecular Formula
C24H29N5O2
Molecular Weight
419.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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