Antioxidant agent-5

• Target:

  Apoptosis|||Reactive Oxygen Species|||NF-?B|||Others|||Nrf2

• Related Pathways:

  Metabolism|||Apoptosis|||NF-?B|||Others|||Immunology/Inflammation

• Bioactivity:

  Antioxidant agent-5 (compound D-6) is a potent antioxidant that inhibits oxLDL-induced increases in ROS levels and NF-?B nuclear translocation. It also prevents oxLDL (oxidized LDL) -induced apoptosis (VECs), activates the Nrf2/HO-1 antioxidant pathway, and exhibits protective activity against oxLDL-induced endothelial damage.

• Smiles:

  C(C=1C=2C(NC1)=CC=CC2)C3=NC(CN4CCN(CC5=CC=C(C#N)C=C5)CC4)=NO3

• Molecular Formula:

  C24H24N6O

• Molecular Weight:

  412.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2684291-60-7