C-ABL-IN-4

CAT: 0931-MF-0048907-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0048907-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2626934-68-5
Target
Others|||Bcr-Abl
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Others
Bioactivity
C-ABL-IN-4, a potent inhibitor of c-Abl, exhibits strong activity in inhibiting the Bcr-Abl (IC50 = 4.5 nM) kinase activity and proliferation (IC50 = 0.41-2.12 ?M) of Bcr-Abl (T315I) cell lines.
Smiles
O=C1N(C=C(C(NC2=CC=C(OC(Cl)(F)F)C=C2)=O)C=C1)C=3C=C(F)C=NC3
Molecular Formula
C18H11ClF3N3O3
Molecular Weight
409.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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