C-ABL-IN-4

CAT: 0931-T62065-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T62065-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2626934-68-5

Target

Others, Bcr-Abl

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Others

Bioactivity

C-ABL-IN-4, a potent inhibitor of c-Abl, exhibits strong activity in inhibiting the Bcr-Abl (IC50 = 4.5 nM) kinase activity and proliferation (IC50 = 0.41-2.12 μM) of Bcr-Abl (T315I) cell lines.

Smiles

O=C1N(C=C(C(NC2=CC=C(OC(Cl)(F)F)C=C2)=O)C=C1)C=3C=C(F)C=NC3

Molecular Formula

C18H11ClF3N3O3

Molecular Weight

409.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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C-ABL-IN-4

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