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MTOR/HDAC6-IN-1

CAT: 0931-T61888-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61888-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, mTOR, Autophagy, Apoptosis, HDAC
Related Pathways
Autophagy, Others, Chromatin/Epigenetic, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Apoptosis
Bioactivity
MTOR/HDAC6-IN-1 is an effective dual inhibitor of histone deacetylase (HDAC6) and mammalian rapamycin (mTOR) . The IC50 values for HDAC6 and mTOR are 56 nM and 133.7 nM respectively. MTOR/HDAC6-IN-1 can significantly induce autophagy and apoptosis and inhibit migration. MTOR/HDAC6-IN-1 has potential in the study of triple negative breast cancer (TNBC) .
Molecular Formula
C20H20ClN5O2
Molecular Weight
397.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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