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Orantinib

CAT: 0931-T6184-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T6184-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
252916-29-3
Target
PDGFR, FGFR, VEGFR, Apoptosis
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
Orantinib (NSC 702827), a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
Smiles
Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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