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M1002

CAT: 0931-T61822-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T61822-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
823830-85-9
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Chromatin/Epigenetic, Metabolism, Angiogenesis
Purity
0.9998
Bioactivity
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD) .
Smiles
FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F
Molecular Formula
C15H8F6N2O2S
Molecular Weight
394.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
GTR19186701-01M1002

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