AMS-17

• Target:

  Others|||NOD-like Receptor (NLR)

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  AMS-17 is a potent NLRP3 inhibitor that effectively suppresses microglia activation both in vitro and in vivo. Moreover, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-?, IL-1?, and inducible nitric oxide synthase (iNOS), in N9 cells, making it a promising tool for investigating inflammation-associated neurological disorders [1].

• Molecular Formula:

  C15H13F3N4O3S

• Molecular Weight:

  386.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C