AMS-17

CAT: 0931-T61709-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61709-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Others, NOD-like Receptor (NLR)

Related Pathways

Others, Immunology/Inflammation

Bioactivity

AMS-17 is a potent NLRP3 inhibitor that effectively suppresses microglia activation both in vitro and in vivo. Moreover, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-α, IL-1β, and inducible nitric oxide synthase (iNOS), in N9 cells, making it a promising tool for investigating inflammation-associated neurological disorders [1].

Molecular Formula

C15H13F3N4O3S

Molecular Weight

386.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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