Leu-AMS

CAT: 0931-T11840-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T11840-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

288591-93-5

Target

Antibacterial, Others

Related Pathways

Microbiology/Virology, Others

Bioactivity

Leu-AMS, a leucine analogue and potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, exhibits cytotoxic effects in both cancer and normal cells and hampers bacterial growth. It specifically inhibits LRS's catalytic activity without impacting the leucine-induced activation of mTORC1.

Smiles

CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

Molecular Formula

C16H25N7O7S

Molecular Weight

459.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA1254-1	Leu-AMS
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A19580-25	Leu-AMS 25mg
A19580-10	Leu-AMS 10mg
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A19580-100	Leu-AMS 100mg
A19580-1	Leu-AMS 1mg
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