VPC-13789

• Target :

  Others|||Androgen Receptor

• Related Pathways :

  Endocrinology/Hormones|||Others

• Bioactivity :

  VPC-13789 is a highly potent, selective, and orally bioavailable antiandrogen compound that shows promise for studying and developing therapeutics for castration-resistant prostate cancer (CRPC) . In LNCaP cells, VPC-13789 effectively inhibits the transcriptional activity of the androgen receptor (AR) with an IC50 value of 0.19 ?M [1].

• Smiles :

  FC1=C2C(C(=CN2)C3=NC4=C(C=C3)C(C(NC(C)C)=O)=CC=C4)=CC(F)=C1F

• Molecular Formula :

  C21H16F3N3O

• Molecular Weight :

  383.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2761146-51-2