NHE3-IN-3

CAT: 0931-T61480-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61480-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

543734-50-5

Target

Others, Sodium Channel

Related Pathways

Others, Membrane transporter/Ion channel

Bioactivity

NHE3-IN-3 (Compound 1) is a potent inhibitor of isoform 3 of the Na+/H+ exchanger (NHE3), exhibiting pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively, and demonstrates exceptional oral bioavailability of 98% in Sprague–Dawley rats [1].

Smiles

CN1CC(C=2C(C1)=C(Cl)C=C(Cl)C2)C3=CC(S(N)(=O)=O)=CC=C3

Molecular Formula

C16H16Cl2N2O2S

Molecular Weight

371.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19187062-01	NHE3-IN-3
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