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Thioridazine

CAT: 0931-T61476-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T61476-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-52-2
Target
5-HT Receptor, Apoptosis, Dopamine Receptor, Autophagy, Others, Antibacterial
Related Pathways
Apoptosis, Microbiology/Virology, GPCR/G Protein, Others, Autophagy, Neuroscience
Bioactivity
Thioridazine is a chemical compound characterized by its potent anti-psychotic and anti-anxiety activities. As an antagonist of the dopamine receptor D2 family proteins, it exhibits a strong inhibitory effect on the PI3K-Akt-mTOR signaling pathways, resulting in anti-angiogenic effects. It also demonstrates significant antiproliferative and apoptosis induction effects in a diverse range of cancer cells, specifically targeting cancer stem cells (CSCs) [1] [2] [3] [4].
Smiles
CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1
Molecular Formula
C21H26N2S2
Molecular Weight
370.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C