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Pralatrexate

CAT: 0931-T6120-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6120-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
146464-95-1
Target
DHFR, Apoptosis, Antifolate, TAM Receptor
Related Pathways
Cell Cycle/Checkpoint, Metabolism, Apoptosis, DNA Damage/DNA Repair, Tyrosine Kinase/Adaptors
Purity
0.9959
Bioactivity
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
Smiles
Nc1nc(N)c2nc(CC(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
Molecular Formula
C23H23N7O5
Molecular Weight
477.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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