Torin 2

• Target :

  DNA-PK|||Apoptosis|||mTOR|||ATM/ATR|||Autophagy

• Related Pathways :

  DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling|||Autophagy|||Apoptosis

• Purity :

  0.9947

• Bioactivity :

  Torin 2 (IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 28 nM/35 nM/118 nM, respectively.

• Smiles :

  Nc1ccc(cn1)-c1ccc2ncc3ccc(=O)n(-c4cccc(c4)C(F)(F)F)c3c2c1

• Molecular Formula :

  C24H15F3N4O

• Molecular Weight :

  432.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1223001-51-1