LY-411575

• Target :

  Apoptosis|||Gamma-secretase

• Related Pathways :

  Neuroscience|||Stem Cells|||Apoptosis|||Proteases/Proteasome

• Purity :

  0.9938

• Bioactivity :

  LY-411575, a potent ?-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.

• Smiles :

  C[C@H](NC(=O)[C@@H](O)c1cc(F)cc(F)c1)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O

• Molecular Formula :

  C26H23F2N3O4

• Molecular Weight :

  479.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  209984-57-6