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LY-411575

CAT: 0931-T6063-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T6063-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
209984-57-6
Target
Apoptosis, Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Apoptosis, Proteases/Proteasome
Purity
0.9938
Bioactivity
LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
Smiles
C[C@H](NC(=O)[C@@H](O)c1cc(F)cc(F)c1)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O
Molecular Formula
C26H23F2N3O4
Molecular Weight
479.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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