LY-411575

• Target:

  Apoptosis|||Gamma-secretase

• Related Pathways:

  Neuroscience|||Stem Cells|||Apoptosis|||Proteases/Proteasome

• Purity:

  0.9938

• Bioactivity:

  LY-411575, a potent ?-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.

• Smiles:

  C[C@H] (NC (=O) [C@@H] (O) c1cc (F) cc (F) c1) C (=O) N[C@H]1c2ccccc2-c2ccccc2N (C) C1=O

• Molecular Formula:

  C26H23F2N3O4

• Molecular Weight:

  479.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  209984-57-6