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MPT0G211

CAT: 0931-T60616-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T60616-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2151853-97-1
Target
HDAC
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9998
Bioactivity
MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human breast cancer cells. MPT0G211 has 1,000 times more affinity for HDAC6 than other HDAC subtypes. MPT0G211 can cross the blood-brain barrier and could be used to improve tau phosphorylation and cognitive deficits in Alzheimer's disease models.
Smiles
ONC(=O)c1ccc(CNc2cccc3cccnc23)cc1
Molecular Formula
C17H15N3O2
Molecular Weight
293.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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