TAK-285

• Target :

  EGFR|||HER|||Aurora Kinase|||MEK

• Related Pathways :

  Cell Cycle/Checkpoint|||Angiogenesis|||MAPK|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Chromatin/Epigenetic

• Purity :

  0.9973

• Bioactivity :

  TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.

• Smiles :

  CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12

• Molecular Formula :

  C26H25ClF3N5O3

• Molecular Weight :

  547.96

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  871026-44-7