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TAK-285

CAT: 0931-T6039-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6039-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
871026-44-7
Target
EGFR, HER, Aurora Kinase, MEK
Related Pathways
Cell Cycle/Checkpoint, Angiogenesis, MAPK, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic
Purity
0.9973
Bioactivity
TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
Smiles
CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12
Molecular Formula
C26H25ClF3N5O3
Molecular Weight
547.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-15196-01TAK-285
sc-364627ATAK 285

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