UMI-77

• Target:

  Bcl-2 Family

• Related Pathways:

  Apoptosis

• Purity:

  0.9957

• Bioactivity:

  UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1 with a Ki of 490 nM and is selective over other members of the Bcl-2 family.

• Smiles:

  OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O

• Molecular Formula:

  C18H14BrNO5S2

• Molecular Weight:

  468.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  518303-20-3