UMI-77

• Target :

  Bcl-2 Family

• Related Pathways :

  Apoptosis

• Purity :

  0.9957

• Bioactivity :

  UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1 with a Ki of 490 nM and is selective over other members of the Bcl-2 family.

• Smiles :

  OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O

• Molecular Formula :

  C18H14BrNO5S2

• Molecular Weight :

  468.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  518303-20-3