CFT7455

• Target:

  Ligand for E3 Ligase|||IKZF|||Molecular Glues

• Related Pathways:

  Immunology/Inflammation|||PROTAC

• Purity:

  0.9793

• Bioactivity:

  CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3) .

• Smiles:

  [H][C@@]1(CCC(=O)NC1=O)N1C(=O)c2cccc3c(Cc4ccc(CN5CCOCC5)cc4)ccc1c23

• Molecular Formula:

  C28H27N3O4

• Molecular Weight:

  469.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2504235-67-8