Larotrectinib

• Target :

  Apoptosis|||Trk receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Apoptosis

• Purity :

  >99.99%

• Bioactivity :

  Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM) .

• Smiles :

  O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F

• Molecular Formula :

  C21H22F2N6O2

• Molecular Weight :

  428.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1223403-58-4