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Larotrectinib

CAT: 0931-T5995-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5995-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1223403-58-4
Target
Apoptosis, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
>99.99%
Bioactivity
Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM) .
Smiles
O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Molecular Formula
C21H22F2N6O2
Molecular Weight
428.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C