Larotrectinib

• Target:

  Apoptosis|||Trk receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Apoptosis

• Purity:

  >99.99%

• Bioactivity:

  Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM) .

• Smiles:

  O[C@H]1CCN (C1) C (=O) Nc1cnn2ccc (nc12) N1CCC[C@@H]1c1cc (F) ccc1F

• Molecular Formula:

  C21H22F2N6O2

• Molecular Weight:

  428.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1223403-58-4