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GS-443902

CAT: 0931-T5539-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5539-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1355149-45-9
Target
Drug Metabolite, DNA/RNA Synthesis, HCV Protease, Nucleoside Antimetabolite/Analog, SARS-CoV, RSV
Related Pathways
Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Proteases/Proteasome, Microbiology/Virology
Bioactivity
Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.
Smiles
Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
Molecular Formula
C12H16N5O13P3
Molecular Weight
531.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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