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Pristimerin

CAT: 0931-T4S1050-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4S1050-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1258-84-0
Target
NF-κB, Antibacterial
Related Pathways
NF-κB, Microbiology/Virology
Purity
0.9979
Bioactivity
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
Smiles
COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
Molecular Formula
C30H40O4
Molecular Weight
464.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
256324-01Pristimerin
HY-N1937RPristimerin (Standard)

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