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WHI-P97 HCl

CAT: 0931-T4657L-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T4657L-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
JAK
Related Pathways
Stem Cells, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis
Purity
0.9949
Bioactivity
WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. WHI-P97 effectively inhibited the in vitro invasiveness of EGFR-positive human cancer cells in a concentration-dependent manner.
Smiles
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)Br)O)Br)OC.Cl
Molecular Formula
C16H14Br2ClN3O3
Molecular Weight
491.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A11608-5WHI-P97 5mg

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