Licochalcone D

• Target :

  NF-?B|||Apoptosis|||Reactive Oxygen Species|||ERK|||ROS

• Related Pathways :

  Metabolism|||Apoptosis|||Immunology/Inflammation|||NF-?B|||MAPK

• Purity :

  0.999

• Bioactivity :

  Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.

• Smiles :

  COc1c(O)c(O)ccc1\C=C\C(=O)c1ccc(O)c(CC=C(C)C)c1

• Molecular Formula :

  C21H22O5

• Molecular Weight :

  354.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  144506-15-0