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E7449

CAT: 0931-T4471-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4471-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1140964-99-3
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.97816
Bioactivity
E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
Smiles
O=c1[nH][nH]c2nc(CN3Cc4ccccc4C3)nc3cccc1c23
Molecular Formula
C18H15N5O
Molecular Weight
317.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS3845983-01E7449
C13406-1gStenoparib (E7449)
A21553-10E7449 10mg
A21553-100E7449 100mg
A21553-5E7449 5mg
A21553-50E7449 50mg
A21553-200Stenoparib (E7449) 200mg
A21553-1Stenoparib (E7449) 1mg
A21553-25Stenoparib (E7449) 25mg
A21553-10mM-DStenoparib (E7449) 10mM * 1mL in DMSO

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