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Gilteritinib

CAT: 0931-T4409-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4409-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1254053-43-4
Target
C-Kit, FLT, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.999
Bioactivity
Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively) . In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia.
Smiles
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1
Molecular Formula
C29H44N8O3
Molecular Weight
552.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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