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Prexasertib

CAT: 0931-T4310-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4310-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1234015-52-1
Target
Apoptosis, Chk
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM) . Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity.
Smiles
COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Molecular Formula
C18H19N7O2
Molecular Weight
365.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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