Prexasertib

• Target :

  Apoptosis|||Chk

• Related Pathways :

  Apoptosis|||Cell Cycle/Checkpoint

• Purity :

  >99.99%

• Bioactivity :

  Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM) . Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity.

• Smiles :

  COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

• Molecular Formula :

  C18H19N7O2

• Molecular Weight :

  365.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1234015-52-1