AC-264613

• Target :

  Protease-activated Receptor

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2) . AC-264613 (AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613 (AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca (2+) mobilization assays, with potencies ranging from 30 to 100 nM.

• Smiles :

  CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1

• Molecular Formula :

  C19H18BrN3O2

• Molecular Weight :

  400.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1051487-82-1