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AC-264613

CAT: 0931-T4186-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4186-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1051487-82-1
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2) . AC-264613 (AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613 (AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca (2+) mobilization assays, with potencies ranging from 30 to 100 nM.
Smiles
CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1
Molecular Formula
C19H18BrN3O2
Molecular Weight
400.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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