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BPTU

CAT: 0931-T4132-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4132-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
870544-59-5
Target
P2Y Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9989
Bioactivity
BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM) . Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.
Smiles
CC(C)(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
Molecular Formula
C23H22F3N3O3
Molecular Weight
445.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C