Thalidomide-NH-PEG8-Ts

CAT: 0931-MF-0138747-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0138747-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2488761-07-3
Target
Others|||E3 Ligase Ligand-Linker Conjugate|||Autophagy|||Apoptosis
Related Pathways
PROTAC|||Apoptosis|||Others|||Autophagy
Bioactivity
Thalidomide-NH-PEG8-Ts is a chemically synthesized conjugate comprised of a Thalidomide-based cereblon ligand and an 8-unit PEG linker, functioning as an E3 ligase ligand-linker in PROTAC technology applications, such as the degradation of IDO1 by a PROTAC degrader.
Smiles
Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Molecular Formula
C36H49N3O14S
Molecular Weight
779.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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