CBR-470-1

CAT: 0931-MF-0050516Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0050516Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2416095-06-0
Target
PGK1|||Nrf2
Related Pathways
Immunology/Inflammation|||Metabolism
Purity
0.9887
Bioactivity
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.
Smiles
S(=O)(=O)([C@@H]1[C@@H](NCC(C)C)CS(=O)(=O)C1)C2=CC=C(Cl)C=C2
Molecular Formula
C14H20ClNO4S2
Molecular Weight
365.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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