MS98

CAT: 0931-T39930Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T39930Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2376137-31-2

Target

Others, PROTACs, Akt

Related Pathways

Cytoskeletal Signaling, PROTAC, PI3K/Akt/mTOR signaling, Others

Bioactivity

MS98 is a highly effective and specific PROTAC AKT degrader compound that effectively targets and depletes total AKT (T-AKT) within cells, exhibiting a DC 50 value of 78 nM. This compound readily binds to AKT1, AKT2, and AKT3 with respective dissociation constants (Kd s) of 4 nM, 140 nM, and 8.1 nM.

Smiles

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCCCC(=O)NCCNC[C@@H](C(=O)N1CCN(CC1)c1ncnc2[C@H](O)C[C@@H](C)c12)c1ccc(Cl)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

Molecular Formula

C58H81ClN10O7S

Molecular Weight

1097.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-145281	MS98

MS98

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