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MS21

CAT: 0931-T39929Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T39929Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2376137-05-0
Target
Ras, PROTACs, Akt, Kras
Related Pathways
PROTAC, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, MAPK
Bioactivity
MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.
Smiles
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCC(=O)N2CCN(CC[C@H](NC(=O)C3(N)CCN(CC3)c3ncnc4[nH]ccc34)c3ccc(Cl)cc3)CC2)C(C)(C)C)cc1
Molecular Formula
C58H79ClN12O6S
Molecular Weight
1107.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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